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Microbiology & Infection - Microbiologie & Infection - Microbiologia & Infezione

Authors : Hawley (BRS) Gillespie (Glance) Harvey (LIR) Le (First Aid)

Microorganisms




Microorganisms



Bacteriology



Structures &
Cell Walls

Stains

Growth Media &
Special Culture 

Virulence Factors

Genetics

Exotoxins & Endotoxins

Exotoxins

Endotoxin

Taxonomy
Aerobes
Anaerobes
Intracellular bugs
Encapsulated
Encapsulated Vaccines
Type III secretion system
Spore-Forming In Vivo
Pigment-Producing
Biofilm-Producing


Bacteriology


Bacteria




Bacteria 

Lab Algorithm

Gram+ Lab Algorithm

Gram-
Lab Algorithm

Major Bacterial Genera
G+

Major Bacterial Genera
G-

Major Bacterial Genera
Gpoorly
Catalase-Positive
Urease-Positive
β-hemolytic bacteria
α-hemolytic bacteria
Gram+ cocci antibiotic tests
Lactose-fermenting enteric bacteria
Identification




Staphylococcus
S aureus coag +
S epidermidis coag -
S saprophyticus coag -


Staphylococcus G+



Streptococcus 1

Streptococcus 2
S pneumoniae α
Viridans α
S pyogenes β Group A
S agalactiae β Group B
S bovis γ Group D
Enterococci γ Group D
Group C

Streptococcus G+


Cocci G+




Bacillus
B anthracis
B cereus


Bacillus G+



Clostridia
C tetani
C botulinum
C perfringens
C difficile


Clostridia G+



Corynebacterium diphtheriae

Listeria monocytogenes


Bacilli G+



Nocardia vs Actinomyces



Branching Filaments G+


Gram+



Mycobacteria

Mycobacteria

Primary & Secondary Tuberculosis

Leprosy (Hansen disease)
Mycobacteria Poorly G+




Neisseria &
Moraxella



Neisseria G-



Haemophilus influenzae

Bordetella pertussis


Coccobacilli G-



Comma-Shaped Rods
G-
Campylobacter jejuni
Helicobacter pylori
Vibrio cholerae


Comma-Shaped Rods G-



Enterobacteriaceae




Yersinia enterocolitica

Klebsiella

Salmonella
vs Shigella

Escherichia coli
Enterobacteriaceae




Pseudomonas aeruginosa

Legionella pneumophila


Environmental pathogens



Bacilli G-


Gram-



Spirochetes

Spiral

Syphilis
Leptospira interrogans
Lyme disease
VDRL false positives
Jarisch-Herxheimer reaction
Spirochetes Poorly G



Pleomorphic

Gardnerella vaginalis


Rickettsial D & vector-borne illnesses


Chlamydiae


Chlamydia trachomatis
serotypes

Mycoplasma pneumoniae



Poorly G




Zoonotic



Zoonotic


Bacteria



Bacterial Infections







Bacterial Infections



Mycology



Fungi 

Mycology

Fungal Diseases


Superficial Skin

Cutaneous

Mucocutaneous Candidiasis 


Subcutaneous

Pneumonias/Systemic

Opportunistic
Yeast
Filamentous

Immunocompetent Non Syst Symptoms
Immunocompetent Systemic Symptoms Immunocompromised Symptoms

Mycology



Parasitology


Protozoa



Protozoa 

Protozoa



Gastro-Intestinal 


CNS


Hematologic


Visceral


STI




Protozoa


Helminths



Helminths
Gut
Tissues
Nematode routes of infection
Immune response to helminths
Nematodes (Roundworms)
Cestodes (Tapeworms)
Trematodes (Flukes)
Parasite hints


Helminths


Arthropods Ectoparasites



Ectoparasites
Sarcoptes scabiei
Pediculus humanus / Phthirus pubis


Arthropods Ectoparasites



Parasitology



Virology



Viruses 

Viruses

DNA 

RNA 

Structure - general features


Genetics


Vaccines


Genomes
&
Naked Genome Infectivity
Virology



Viruses



Herpes

HSV identifcation

Negative-stranded
Receptors used
Replication
Envelopes

Herpes


DNA




Reo Rota


Picorna Rhino

Flavi Yellow fever

Flavi Zika

Toga Rubella

Orthomyxo Influenza



Paramyxo
Croup (acute laryngotracheobronchitis)
Measles (rubeola)
Mumps


Paramyxo



Rhabdo Rabies 

Filo Ebola 


RNA



Viruses


Hepatitis Viruses



Hepatitis Viruses

Hepatitis A B C

Serologic Markers
Extrahepatic Manifestations B & C
Hepatitis Viruses



HIV Infection & AIDS



HIV

HIV Diagnosis

Time course of untreated HIV infection

Common diseases of HIV-positive adults
HIV Infection & AIDS



Viral Infections






Viral Infections



Prions




Prions




Prions



Systems



Dominant



Normal Flora




Nosocomial 



Nosocomial 



Immunocompromised



Immunocompromised




Ocular



Eye


Ear


Ear




Heart



Heart




Foodborne &
Diarrhea



Gastrointestinal







Liver




Respiratory

Pneumonia


Respiratory




CNS
CSF Findings in Meningitis
Brain Abscess
Meningitis
 

Nervous System



Bones & Joints
Osteomyelitis

Bones & Joints




UTI
s
UTI bugs

Vaginal


UTIs



STIs

Pelvic inflammatory disease


STIs


Urinary & Genital




Red Rashes of Childhood


Unvaccinated Children

ToRCHeS

Children




Skin, Mucosal & Soft Tissues



Skin, Mucosal & Soft Tissues




Bug Hints (if all else fails)



Systems



Antimicrobial


Antibacterial therapy
Penicillin G, V
Penicillinase-sensitive penicillins
Penicillinase-resistant penicillins
Antipseudomonal penicillins
β-lactamase inhibitors
Cephalosporins (generations I–V)
Carbapenems
Monobactams
Vancomycin
Protein synthesis inhibitors
Aminoglycosides
Tetracyclines
Glycylcyclines
Chloramphenicol
Clindamycin
Oxazolidinones
Macrolides
Sulfonamides
Dapsone
Trimethoprim
Fluoroquinolones
Daptomycin
Metronidazole
Antimycobacterial drugs
Rifamycins
Isoniazid
Pyrazinamide
Ethambutol
Streptomycin
Antimicrobial prophylaxis
Prophylaxis in HIV patients
Treatment of highly resistant bacteria



Antibacterial



Antifungal therapy
Amphotericin B
Nystatin
Flucytosine
Azoles
Terbinafne
Echinocandins
Griseofulvin
Antifungal



Antiprotozoan therapy
Anti-mite/louse therapy
Chloroquine

Antiprotozoan 



Antihelminthic therapy


Antihelminthic



Oseltamivir, zanamivir
Acyclovir, famciclovir, valacyclovir
Ganciclovir
Foscarnet
Cidofovir
HIV therapy
Interferons
Hepatitis C therapy
Disinfection and sterilization



Antiviral



Antimicrobials to avoid in pregnancy



Antimicrobial



Topics
Links & References
Authors :

Hawley. BRS Microbiology & Immunology. 6e. 2013.

Gillespie. Medical Microbiology & Infection at a Glance. 4e. 2012.


Harvey. LIR Microbiology. 3e. 2013.


Le. First Aid USMLE Step 1. 2017. (Microbiology)

Moi :
Bacteria 1 / Bacteria 2
Viruses 1 / Viruses 2
Fungi 1 / Fungi 2
Protozoa 1 / Protozoa 2

Prion