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Le. First Aid USMLE Step 1. Hematology & Oncology. 30e. 2020.

00 CONTENTS
01 EMBRYOLOGY
Fetal erythropoiesis
Blood groups
Hemolytic disease of the newborn
02 ANATOMY
Hematopoiesis
Neutrophils
Erythrocytes
Thrombocytes (platelets)
Monocytes
Macrophages
Eosinophils
Basophils
Mast cells
Dendritic cells
Lymphocytes
Natural killer cells
B cells
T cells
Plasma cells
03 PHYSIOLOGY
Hemoglobin electrophoresis
Platelet plug formation (primary hemostasis)
Thrombogenesis
Coagulation and kinin pathways
Vitamin K–dependent coagulation
04 PATHOLOGY
RBC morphology
RBC inclusions
Anemias
Reticulocyte index
Microcytic,hypochromic anemias
Interpretation of iron studies
Macrocytic anemias
Normocytic,normochromic anemias
Nonhemolytic, normocytic anemias
Intrinsic hemolytic anemias
Extrinsic hemolytic anemias
Leukopenias
Neutrophil left shift
Heme synthesis,porphyrias, and lead poisoning
Iron poisoning
Coagulation disorders
Platelet disorders
Thrombotic microangiopathies
Mixed platelet and coagulation disorders
Hereditary thrombosis syndromes leading to hypercoagulability
Blood transfusion therapy
Leukemia vs lymphoma
Hodgkin vs non‑Hodgkin lymphoma
Hodgkin lymphoma
Non‑Hodgkin lymphoma
Plasma cell dyscrasias
Myelodysplastic syndromes
Leukemias
Chronic myeloproliferative disorders
Polycythemia
Chromosomal translocations
Langerhans cell histiocytosis
Tumor lysis syndrome
Hemophagocytic lymphohistiocytosis
05 PHARMACOLOGY
Direct thrombin inhibitors
Heparin
Warfarin
Heparin vs warfarin
Direct factor Xa inhibitors
Thrombolytics
ADP receptor inhibitors
Glycoprotein IIb/IIIa inhibitors
Cancer therapy—cell cycle
Cancer therapy—targets
Antitumor antibiotics
Antimetabolites
Alkylating agents
Microtubule inhibitors
Cisplatin, carboplatin, oxaliplatin
Etoposide, teniposide
Irinotecan, topotecan
Hydroxyurea
Bevacizumab
Erlotinib
Cetuximab, panitumumab
Imatinib, dasatinib, nilotinib
Rituximab
Bortezomib, carfilzomib
Tamoxifen, raloxifene
Trastuzumab
Dabrafenib, vemurafenib
Rasburicase
Key chemotoxicities