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Le. First Aid USMLE Step 1. Immunology. 30e. 2020.
CONTENTS
LYMPHOID STRUCTURES
Immune system organs
Lymph nodes
Lymphatic drainage associations
Spleen
Thymus
CELLULAR COMPONENTS
Innate Immunity
Adaptive Immunity
Innate vs adaptive immunity
Passive Immunity
Major histocompatibility complex I and II
HLA subtypes associated with diseases
Functions of Natural killer cells
Major functions of B and T cells
Differentiation of T cells
T cell subsets
Macrophage-lymphocyte interaction
Cytotoxic T cells
Regulatory T cells
T- and B-cell activation
IMMUNE RESPONSES
Acute-phase reactants
Antibody structure & function
Immunoglobulin isotypes
Antigen type and memory
Complement
Complement disorders
Important cytokines
Respiratory burst (oxidative burst)
Interferon-α and -β
Cell surface proteins
Anergy
Passive vs active immunity
Vaccination
Hypersensitivity types
Blood transfusion reactions
Autoantibodies
Immunodeficiencies
Infections in immunodeficiency
Grafts
Transplant rejection
IMMUNOSUPPRESSANTS
Immunosuppressants
Immunosuppression targets
Recombinant cytokines and clinical uses
Therapeutic antibodies