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Silbernagl. Atlas of Pathophysiology. 3e. 2016.
 
0 Contents
1 Fundamentals
Cell Growth and Cell Adaptation
Abnormalities of Intracellular Signal Transmission
PI3-Kinase-Dependent Signal Transduction
Necrotic Cell Death
Apoptotic Cell Death
Development of Tumor Cells
Effects of Tumors
Aging and Life Expectancy
2 Temperature, Energy
Fever
Hyperthermia, Heat Injuries
Hypothermia, Cold Injury
3 Blood
Overview
Erythrocytes
Erythropoiesis, Anemia
Erythrocyte Turnover: Abnormalities, Compensation, and Diagnosis
Megaloblastic Anemia Due to Abnormalities in DNA Synthesis
Anemias Due to Disorders of Hemoglobin Synthesis
Iron Deficiency Anemia
Hemolytic Anemias
Malaria
Immune Defense
Inflammation
Hypersensitivity Reactions (Allergies)
Autoimmune Diseases
Immune Defects
Hemostasis and Its Disorders
4 Respiration, Acid-Base Balance
Overview
Ventilation, Perfusion
Diffusion Abnormalities
Distribution Abnormalities
Restrictive Lung Diseases
Obstructive Lung Diseases
Pulmonary Emphysema
Pulmonary Edema
Pathophysiology of Breathing Regulation
Acute Respiratory Distress Syndrome
Hypoxia
Hyperoxia, Oxidative Stress
Development of Alkalosis
Development of Acidosis
Effects of Acidosis and Alkalosis
5 Kidney, Salt and Water Balance
Overview
Abnormalities of Renal Excretion
Pathophysiology of Renal Transport Processes
Abnormalities of Urinary Concentration
Polycystic Kidney Disease
Abnormalities of Glomerular Function
Disorders of Glomerular Permselectivity, Nephrotic Syndrome
Interstitial Nephritis
Acute Renal Failure
Chronic Renal Failure
Renal Hypertension
Kidney Disease in Pregnancy
Hepatorenal Syndrome
Urolithiasis
Disorders of Water and Salt Balance
Abnormalities of Potassium Balance
Abnormalities of Magnesium Balance
Abnormalities of Calcium Balance
Abnormalities of Phosphate Balance
Pathophysiology of Bone
6 Stomach, Intestines, Liver
Function of the Gastrointestinal Tract
Esophagus
Nausea and Vomiting
Gastritis (Gastropathy)
Ulcer
Disorders after Stomach Surgery
Diarrhea
Maldigestion and Malabsorption
Constipation and (Pseudo-)Obstruction
Chronic Inflammatory Bowel Disease
Acute Pancreatitis
Chronic Pancreatitis
Cystic Fibrosis
Gallstone Disease (Cholelithiasis)
Jaundice (Icterus) and Cholestasis
Portal Hypertension
Fibrosis and Cirrhosis of the Liver
Liver Failure
7 Heart and Circulation
Overview
Phases of Cardiac Action (Cardiac Cycle)
Origin & Spread of Excitation in the Heart
The Electrocardiogram (ECG)
Abnormalities of Cardiac Rhythm
Mitral Stenosis
Mitral Regurgitation
Aortic Stenosis
Aortic Regurgitation
Defects of the Tricuspid and Pulmonary Valves
Circulatory Shunt
Arterial Blood Pressure and Its Measurement
Hypertension
Pulmonary Hypertension
Coronary Circulation
Coronary Heart Disease
Myocardial Infarction
Heart Failure
Pericardial Diseases
Circulatory Shock
Edema
Atherosclerosis
Nonatherosclerotic Disturbances of Arterial Bloodflow
Venous Diseases
8 Metabolic Disorders
Overview
Disorders of Amino Acid Metabolism
Disorders of Carbohydrate Metabolism
Lipidoses
Abnormalities of Lipoprotein Metabolism
Energy Homeostasis, Obesity
Eating Disorders
Gout
Iron Metabolism, Hemochromatosis
Copper Metabolism, Wilson's Disease
a1-Antitrypsin Deficiency
Dysproteinemias
Heme Synthesis, Porphyrias
9 Hormones
General Pathophysiology of Hormones
Abnormalities of Endocrine Regulatory Circuits
Antidiuretic Hormone
Prolactin
Somatotropin
Adrenocortical Hormones: Enzyme Defects in Production
Adrenocortical Hormones: Causes of Abnormal Secretion
Excess Adrenocortical Hormones: Cushing's Disease
Deficiency of Adrenocortical Hormones: Addison's Disease
Causes and Effects of Androgen Excess and Deficiency
Female Sex Hormone Secretion
Effects of Female Sex Hormones
Intersexuality
Causes of Hypothyroidism, Hyperthyroidism, and Goiter
Effects and Symptoms of Hyperthyroidism
Effects and Symptoms of Hypothyroidism
Causes of Diabetes Mellitus
Acute Effects of Insulin Deficiency (Diabetes Mellitus)
Late Complications of Prolonged Hyperglycemia (Diabetes Mellitus)
Hyperinsulinism, Hypoglycemia
Histamine, Bradykinin, and Serotonin
Eicosanoids
10 Neuromuscular and Sensory Systems
Overview
Pathophysiology of Nerve Cells
Demyelination
Disorders of Neuromuscular Transmission
Diseases of the Motor Unit and Muscles
Lesions of the Descending Motor Tracts
Diseases of the Basal Ganglia
Lesions of the Cerebellum
Abnormalities of the Sensory System
Pain
Diseases of the Optical Apparatus of the Eye
Diseases of the Retina
Abnormalities of the Visual Pathway and Processing of Visual Information
Hearing Impairment
Vestibular System, Nystagmus
Olfaction, Taste
Disorders of the Autonomic Nervous System
Lesions of the Hypothalamus
The Electroencephalogram (EEG)
Epilepsy
Sleep Disorders
Consciousness
Aphasia
Disorders of Memory
Alzheimer's Disease, Dementia
Depression
Schizophrenia
Dependence, Addiction
Cerebrospinal Fluid, Blood-Brain Barrier
Cerebrospinal Fluid Pressure, Cerebral Edema
Disorders of Cerebral Blood Flow, Stroke