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Neurology & Special Senses - Neurologie - Neurologia

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REFERENCES

CONTENTS :
- OTOLOGY
- OPHTHALMOLOGY
- PHARMACOLOGY

EMBRYOLOGY, HISTOLOGY, ANATOMY & PHYSIOLOGY
EMBRYOLOGY
ASSESSMENT INVESTIGATIONS
PATHOLOGY SYMPTOMS
INFECTION


OTOLOGY
OPHTHALMOLOGY
PHARMACOLOGY

TOC
MAPS

TOC
EMBRYOLOGY, HISTOLOGY, ANATOMY & PHYSIOLOGY

TOC
EMBRYOLOGY

NEURAL DEVELOPMENT
Gastrulation
NEURULATION
NEURAL TUBE DEFECTS
Spinal dysraphism
Spina bifida occulta
Meningocele
Myelomeningocele

Myeloschisis
Cranial dysraphism
Anencephaly

CROSS-SECTION OF THE NEURAL TUBE
REGIONALIZATION OF NEURAL TUBE
CENTRAL & PERIPHERAL NERVOUS SYSTEMS ORIGINS


BRAIN DEVELOPMENT
FORMATION OF BRAIN VESICLES
BRAIN MALFORMATIONS

Holoprosencephaly
Lissencephaly
Hydrocephalus
Microcephaly
POSTERIOR FOSSA MALFORMATIONS
Chiari I malformation
Chiari II malformation
Dandy-Walker malformation syndrome

SYRINGOMYELIA

TONGUE DEVELOPMENT


TOC
HISTOLOGY
CELLS OF THE NERVOUS SYSTEM
Neurons
Neuroglia

Astrocytes
Microglia
Ependymal cells
Myelin
Schwann cells
Oligodendrocytes

NEURON ACTION POTENTIAL
INTERCELLULAR COMMUNICATION

Synapses
Neuromuscular Junction

Diseases of the Neuromuscular Junction
SENSORY CORPUSCLES RECEPTORS
Free nerve endings
Meissner corpuscles
Pacinian corpuscles
Merkel discs
Ruffini corpuscles

ORGANIZATION OF PERIPHERAL NERVES
CHROMATOLYSIS
Wallerian degeneration
NEUROTRANSMITTER CHANGES WITH DISEASE
Acetylcholine
Dopamine
GABA
Norepinephrine
Serotonin


MENINGES
Pathology of the Meninges
Epidural Hemorrhage
Subdural Hemorrhage
Subarachnoid Hemorrhage
Meningitis
Meningioma
Carcinomatous Meningitis

BLOOD-BRAIN BARRIER

VOMITING CENTER

SLEEP PHYSIOLOGY

VENTRICLES
Ventricular System
Hydrocephalus
Noncommunicating hydrocephalus
Communicating hydrocephalus
Normal-pressure hydrocephalus
Hydrocephalus ex vacuo
Pseudotumor cerebri


BLOOD SUPPLY
Circle of Willis
Dural Veins & Sinuses
Venous sinus thrombosis
Cerebral perfusion
Homunculus
Cerebral arteries—cortical distribution
Watershed zones

CEREBRAL CORTEX REGIONS
Organization
Frontal Lobe
Parietal Lobe
Occipital Lobe
Temporal Lobes


Cerebral perfusion

Homunculus

DEEP BRAIN STRUCTURES

BASAL GANGLIA

THALAMUS

INTERNAL CAPSULE

HYPOTHALAMUS
Diseases of the Hypothalamus
Central diabetes insipidus
Syndrome of inappropriate ADH (SIADH)
Craniopharyngioma
Pituitary adenomas


LIMBIC SYSTEM

CEREBELLUM
Anatomy
Major Pathways
Cerebellar Dysfunction and Syndromes


BRAIN STEM
Dopaminergic pathways

MIDBRAIN
PONS
MEDULLA


NEUROTRANSMITTERS
Acetylcholine
Dopamine
GABA
Norepinephrine
Serotonin


TOC
SPINAL CORD
Blood Supply
Function
Levels of the Spinal Cord
Unique Structures
Myotatic Reflex
Reflexes and Corresponding Levels
Cross-Section of the Spinal Cord
Tracts of the Spinal Cord  Spinal cord & associated tracts Spinal tract anatomy and functions
Corticospinal Tracts
Lateral corticospinal tract
Ventral corticospinal tract
Hypothalamospinal tract
Other motor tracts
Sensory Pathways
Dorsal column–medial lemniscus pathway
Sensory receptors
First-order neurons
Second-order neurons
Third-order neurons
Lateral spinothalamic tract
Clinical reflexes
Primitive reflexes
Landmark dermatomes
Brown-Séquard Syndrome

Lesions of the Spinal Cord
Spinal cord—lower extent


CRANIAL NERVES
Cranial nerve nuclei
Vagal nuclei
Cranial nerves and vessel pathways
Cranial nerves and arteries
Cranial nerve reflexes
Mastication muscles
Cranial Nerve Lesions


SPINAL NERVES

TOC
SENSORY PATHWAYS
Visual System
Visual Pathway
Auditory System
Auditory Pathway
Hearing Defects

Vestibular System
Labyrinth
Vestibular Pathways

Olfactory System
Olfactory Pathway
Gustatory System
Gustatory Pathway

PATHOLOGY

(Moi Random Old Stuff) V1 PDF

COMMON BRAIN LESIONS
Prefrontal cortex
Frontal eye fields
Paramedian pontine reticular formation
Dominant parietal cortex
Nondominant parietal cortex
Basal ganglia
Subthalamic nucleus
Mammillary bodies
Amygdala
Hippocampus
Dorsal midbrain
Reticular activating system
Medial longitudinal fasciculus
Cerebellar hemisphere
Cerebellar vermis


NEURAL TUBE DEFECTS

VENTRICULAR SYSTEM MALFORMATIONS

HYDROCEPHALUS
NONCOMMUNICATING HYDROCEPHALUS
Dandy-Walker Malformation
Congenital Aqueduct of Sylvius Stenosis
Chiari Malformation
COMMUNICATING HYDROCEPHALUS
Meningitis
Subarachnoid Hemorrhage
-Communicating
-Normal Pressure Hydrocephalus
HYDROCEPHALUS MIMICS
-Ex Vacuo Ventriculomegaly

CEREBROVASCULAR DISORDERS - ISCHEMIC BRAIN DISEASE/STROKE
Ischemic stroke
Thrombotic
Embolic
Hypoxic

Transient ischemic attack
Thrombotic Stroke (Pale Infarction)
Embolic Stroke (Hemorrhagic Infarction)
Intracranial Hemorrhage
Epidural hematoma
Subdural hematoma
Subarachnoid hemorrhage
Intraparenchymal
hemorrhage
Lacunar Infarcts
Stroke Presentation According to Cerebral Location of Occlusion - Effects of strokes
Anterior circulation
Anterior cerebral artery
Middle cerebral artery
Lenticulo-striate artery
Posterior circulation
Posterior cerebral artery
Basilar artery
Anterior inferior cerebellar artery (lateral pontine syndrome)
Posterior inferior cerebellar artery (Wallenberg syndrome/lateral medullary syndrome)
Anterior spinal artery
Neonatal intraventricular hemorrhage
Central poststroke pain
Phantom limb pain
Diffuse axonal injury

Aneurysms
Saccular aneurysm
Charcot-Bouchard microaneurysm

Fever vs heat stroke
Idiopathic intracranial hypertension













ABNORMAL MOTOR POSTURING
Decorticate (flexor) posturing
Decerebrate (extensor) posturing

DYSKINESIAS
Chorea
Diseases Characterized by Chorea
Athetosis
Hemiballismus
MOVEMENT DISORDERS
Akathisia
Asterixis
Athetosis
Chorea
Dystonia
Essential tremor
Intention tremor
Resting tremor
Hemiballismus
Myoclonus
Restless legs syndrome

APHASIAS
Broca (expressive)
Wernicke (receptive)
Conduction
Global

DEGENERATIVE DISEASES
Motor Neuron Lesions
Amyotrophic lateral sclerosis (ALS)
Werdnig-Hoffman disease (infantile spinal muscular atrophy type)
Poliomyelitis
Cerebral Cortex Lesions
-Alzheimer disease
-Frontotemporal dementia (Pick disease)

-Dementia with Lewy bodies (DLB)
Prion diseases (spongiform encephalopathies):
-Creutzfeldt-Jakob disease (CJD),
variant Creutzfeldt-Jakob disease (vCJD),
Kuru,
fatal familial insomnia (FFI)

-Multi-infarct (vascular) dementia
Basal Ganglia Lesions
-Huntington disease
-Parkinson disease (PD)
Wilson disease
Spinocerebellar Lesions
Olivopontocerebellar atrophy
Friedreich ataxia
Progressive Supranuclear Palsy
-HIV-associated dementia
DEMYELINATING DISEASES
-Multiple Sclerosis
Progressive Multifocal Leukoencephalopathy
Acute Disseminated (Postinfectious) Encephalomyelitis
Acute Inflammatory Demyelinating Polyradiculopathy
Osmotic Demyelination Syndrome (Central Pontine Myelinolysis)
Charcot-Marie-Tooth disease
Krabbe disease, metachromatic leukodystrophy, adrenoleukodystrophy
SEIZURES
Partial (one area of the brain) (focal)
Simple partial
Complex partial

Generalized

Absence
Myoclonic
Tonic-clonic
Tonic
Atonic

CEREBRAL EDEMA
Cytotoxic edema
Vasogenic edema
CEREBRAL CONTUSION
PRIMARY BRAIN NEOPLASMS
Adult peak incidence
Glioblastoma multiforme
Hemangioblastoma

Meningioma
Oligodendroglioma
Pinealoma
Schwannoma-neurofibroma

Pituitary Adenomas
Childhood peak incidence
Craniopharyngioma
Ependymoma
Medulloblastoma
Pilocytic astrocytoma
Retinoblastoma

Pineal gland tumors
NEUROCUTANEOUS DISORDERS
Ataxia-telangiectasia (AT, Louis-Bar syndrome)
Sturge-Weber syndrome (SWS)
Tuberous sclerosis complex (TSC)
Neurofibromatosis type 1 (NF1, von Recklinghausen disease)
Neurofibromatosis type 2 (NF2)
von Hippel-Lindau (VHL) syndrome

SPINAL CORD & PERIPHERAL NERVE LESIONS
Motor neuron signs  Comparison of Lower & Upper Motor Neuron Lesions
Weakness
Atrophy
Fasciculations
Reflexes
Tone
Babinski
Spastic paresis
Flaccid paralysis
Clasp knife spasticity

Upper Extremity Nerve Injury
Lower Extremity Nerve Injury
Spinal lesions
Spinal muscular atrophy
Amyotrophic lateral sclerosis
Complete occlusion of anterior spinal artery
Tabes dorsalis
(Tertiary Syphilis)
Syringomyelia
Subacute Combined Degeneration (Vitamin B12 Defciency)
Cauda equina syndrome
Brown-Séquard Syndrome
Poliomyelitis
Thoracic Outlet Syndrome (Klumpke Palsy)
Friedreich ataxia
PERIPHERAL NEUROPATHY
Hereditary Motor and Sensory Neuropathy
CRANIAL NERVE PALSY
Common cranial nerve lesions
CN V motor lesion
CN X lesion
CN XI lesion
CN XII lesion (LMN)

Cranial Nerve Palsies
CN III
CN IV
CN V motor lesion
CN VII
CN X lesion
CN XI lesion
CN XII lesion (LMN)

Defects in Eye Movement
CN III Lesion
CN IV Lesion
CN VI Lesion
Facial Lesions
UMN Lesion
LMN Lesion
Visual Field Defects
Uveitis
Internuclear Ophthalmoplegia (Medial Longitudinal Fasciculus Syndrome)
CENTRAL NERVOUS SYSTEM INFECTIONS
Viral
Bacterial (meningitis)
Fungal
Parasitic
Brain abscess
Meningitis
HERNIATION SYNDROMES
Cingulate (subfalcine) herniation under falx cerebri
Central/downward transtentorial herniation
Uncal transtentorial herniation
Cerebellar tonsillar herniation into the foramen magnum
HEADACHE SYNDROMES
Migraines
Tension-Type Headaches
Cluster Headaches
Trigeminal Neuralgia
OTOLOGY
Auditory anatomy and physiology
Outer ear
Middle ear
Inner ear

Otitis externa
Malignant (necrotizing) otitis externa
Otitis media
Mastoiditis
Common causes of hearing loss
Noise-induced hearing loss
Presbycusis
Diagnosing hearing loss
Normal
Conductive
Sensorineural

Types of hearing loss
Cholesteatoma
Vertigo
Peripheral vertigo
Central vertigo

OPHTHALMOLOGY
Normal eye anatomy
Conjunctivitis
Refractive errors
Hyperopia
Myopia
Astigmatism

Lens disorders
Presbyopia
Cataract

Lens dislocation
Aqueous humor pathway
Trabecular outflow (90%)
Uveoscleral outflow (10%)

Glaucoma
Open-angle glaucoma
Angle-closure glaucoma

Acute angle-closure glaucoma
Retinal disorders
Age-related macular degeneration
Diabetic retinopathy
Hypertensive retinopathy
Retinal artery occlusion
Retinal vein occlusion
Retinal detachment
Retinitis pigmentosa
Papilledema
Leukocoria
Uveitis
Pupillary control
Miosis
Pupillary light reflex
Mydriasis

Relative afferent pupillary defect Marcus Gunn pupil
Horner syndrome
Ocular motility
CN III, IV, VI palsies
CN III damage
CN IV damage
CN VI damage

Visual field defects
Cavernous sinus
Internuclear ophthalmoplegia

PHARMACOLOGY

REFERENCES

Tailor. Neurology and Neurosurgery at a Glance. 1e. 2020.
Le. First Aid USMLE Step 1. Neurology & Special Senses. 32e. 2022. 30e. 2020.
Le. First Aid Basic Sciences Organ Systems. Neurology & Special Senses. 3e. 2017.
Biller. DeMyer's Neurologic Examination. 7e. 2016.
neurology-and-neurosurgery-illustrated-5ed.pdf
neurology-for-non-neurologists-videos-and-pdf

Neurologie Minimum Vital 2002
Caratini.
Collection. Médecine. Neurologie. 1985.

http://medimaps.co.uk/neurology/
http://cim.ucdavis.edu/EyeRelease/Interface/TopFrame.htm
http://www.semep.co.uk/syncope.html

http://library.med.utah.edu/neurologicexam/html/home_exam.html
https://neurologicexam.med.utah.edu/

CLINICAL
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316836/pdf/jnnp-2013-306881.pdf

ANS
https://web.archive.org/web/20181206053244/https://neuroscience.nih.gov/publications/PrinciplesofAutonomicMedicine30.pdf

COGNITIVE DISORDERS
https://mapsontheweb.zoom-maps.com/post/690113454122614784/the-cognitive-disorder-atlas-an-overview-of-the

https://www.reddit.com/r/dataisbeautiful/comments/vzlk46/oc_the_cognitive_disorder_atlas_an_overview_of/
https://www.cognitiveatlas.org/

MORE REFERENCES

Wayback Machine

Tailor. Neurology and Neurosurgery at a Glance. 1e. 2020.
Part 1 General
1 Scalp and skull
2 Essential anatomy: cerebral hemispheres
3 Essential anatomy – subcortical nuclei
4 Essential anatomy of the brain - posterior fossa
5 Essential anatomy – vertebral column
6 Essential anatomy – spinal cord
7 The neurological assessment I - history and cortical function
8 The neurological assessment II - cranial nerves and neuro-opthalmology
9 The neurological assessment III - spine, peripheral nerves, gait and co-ordination
10 Neurological investigations I – CT
11 Neurological investigations II – MRI, MRS and PET
12 Neurological investigations III – NCS, EMG and EEG
Part 2 Common neurological symptoms
13 Headache and facial pain
14 Dizziness and vertigo
15 Seizures and epilepsy
16 Faintness, syncope and coma
17 Weakness and paraesthesia
18 Cognitive impairment and dementia
Part 3 Infection
19 Non-viral infections of the nervous system
20 Viral infections of the nervous system
Part 4 Tumours
21 Brain tumours: basic concepts
22 Brain tumours I
23 Brain tumours II
24 Brain tumours III
25 Spinal tumours
Part 5 Vascular
26 Stroke
27 Subarachnoid haemorrhage and aneurysms
28 Arteriovenous malformations
29 Other vascular lesions
Part 6 Autoimmune and metabolic disorders of the nervous system
30 Multiple sclerosis and other demyelinating diseases
31 Metabolic disorders of the nervous system
Part 7 Trauma
32 Head injuries
33 Intracranial pressure
34 Neurointensive care
35 Spinal injuries
Part 8 Spine
36 Degenerative disease of cervical spine
37 Degenerative disease of thoraco-lumbar spine
38 Autoimmune, metabolic and vascular diseases of the spine
Part 9 Movement disorders
39 Parkinson’s disease and other movement disorders
40 Functional neurosurgery
Part 10 Paediatric
41 Approach to the paediatric patient
42 CSF circulation and hydrocephalus
43 Developmental abnormalities
Part 11 Disorders of nerve and muscle
44 Disease of the peripheral nerves
45 Disease of the muscle
46 Neuromuscular junction and anterior horn cell disorders










NEURAL TUBE DEFECTS




VENTRICULAR SYSTEM MALFORMATIONS
NONCOMMUNICATING HYDROCEPHALUS
Dandy-Walker Malformation
Congenital Aqueduct of Sylvius Stenosis
Chiari Malformation
COMMUNICATING HYDROCEPHALUS
Meningitis
Subarachnoid Hemorrhage
Normal Pressure Hydrocephalus
HYDROCEPHALUS MIMICS
Ex Vacuo Ventriculomegaly
CEREBROVASCULAR DISORDERS
Thrombotic Stroke (Pale Infarction)
Embolic Stroke (Hemorrhagic Infarction)
Intracranial Hemorrhage
Lacunar Infarcts
Stroke Presentation According to Cerebral Location of Occlusion
DYSKINESIAS
Chorea
Diseases Characterized by Chorea
Athetosis
Hemiballismus


APHASIAS
DEGENERATIVE DISEASES
Progressive Supranuclear Palsy
DEMYELINATING DISEASES
Multiple Sclerosis
Progressive Multifocal Leukoencephalopathy
Acute Disseminated (Postinfectious) Encephalomyelitis
Acute Inflammatory Demyelinating Polyradiculopathy
Osmotic Demyelination Syndrome (Central Pontine Myelinolysis)
SEIZURES
CEREBRAL EDEMA CEREBRAL CONTUSION PRIMARY BRAIN NEOPLASMS
Pituitary Adenomas
NEUROCUTANEOUS DISORDERS
SPINAL CORD AND PERIPHERAL NERVE LESIONS
Brown-Séquard Syndrome
Poliomyelitis
Tabes Dorsalis (Tertiary Syphilis)
Subacute Combined Degeneration (Vitamin B12 Defciency)
Syringomyelia
Thoracic Outlet Syndrome (Klumpke Palsy)
PERIPHERAL NEUROPATHY
Hereditary Motor and Sensory Neuropathy
CRANIAL NERVE PALSY
Defects in Eye Movement
CN III Lesion
CN IV Lesion
CN VI Lesion
Facial Lesions
UMN Lesion
LMN Lesion
Visual Field Defects
Uveitis
Internuclear Ophthalmoplegia (Medial Longitudinal Fasciculus Syndrome)
CENTRAL NERVOUS SYSTEM INFECTIONS
Meningitis
HERNIATION SYNDROMES
Cingulate/Subfalcine
Uncal
Cerebellar Tonsillar
Transtentorial
HEADACHE SYNDROMES
Migraines
Tension-Type Headaches
Cluster Headaches
Trigeminal Neuralgia