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Biochemistry - Biochimie - Biochimica

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Phenomenology

Fuel metabolism & Nutrition



Major Pathways 1

Major Pathways 2

Major Pathways 3

Major Pathways 4

Chemistry

Physical chemistry
Basics


Chromatin structure
Nucleotides
De novo pyrimidine &
purine synthesis

Purine salvage defciencies
Genetic code features
DNA replication
Mutations in DNA
DNA repair
Start and stop codons
Functional organization eukaryotic
gene

Regulation of gene expression
RNA polymerases
RNA processing (eukaryotes)
Splicing of pre-mRNA
Introns vs exons
microRNAs
tRNA
Protein synthesis
Posttranslational modifcations
Chaperone protein
Molecular



Cell cycle phases
Rough endoplasmic reticulum
Smooth endoplasmic reticulum
Cell trafcking
Peroxisome
Proteasome
Cytoskeletal elements
IHC stains
 intermediate flaments

Microtubule
Cilia structure
Sodium-potassium pump
Collagen
Collagen synthesis and structure
Osteogenesis imperfecta
Ehlers-Danlos syndrome
Menkes disease
Elastin



Cellular



Polymerase chain reaction
Blotting procedures
Flow cytometry
Microarrays
Enzyme-linked immunosorbent assay
Karyotyping
Fluorescence in situ
hybridization

Cloning methods
Gene expression modifcations



Laboratory Techniques



Genetic terms
Hardy-Weinberg population genetics
Imprinting
Modes of inheritance
Autosomal dominant diseases
Autosomal recessive diseases
Cystic fbrosis
X-linked recessive disorders
Muscular dystrophies
Fragile X syndrome
Trinucleotide repeat expansion
diseases

Autosomal trisomies
Genetic disorders by chromosome
Robertsonian translocation
Cri-du-chat syndrome
Williams syndrome
22q11 deletion syndromes



Genetics



Vitamins: fat soluble Vitamins: water soluble Vitamin A (retinol) Vitamin B1 (thiamine)
Vitamin B2 (riboflavin)
Vitamin B3 (niacin)
Vitamin B5 (pantothenic acid)
Vitamin B6 (pyridoxine)
Vitamin B7 (biotin)
Vitamin B9 (folate)
Vitamin B12 (cobalamin)
Vitamin C (ascorbic acid)
Vitamin D
Vitamin E (tocopherol/tocotrienol)
Vit K
Zinc
Protein-energy malnutrition



Nutrition



Carbohydrates

Lipids

Amino Acids & Proteins

Nucleotides & Nucleic Acids
Biomolecules


Ethanol metabolism
Metabolism sites
Enzyme terminology
Rate-determining enzymes
 metabolic processes
Summary of pathways
ATP production
Activated carriers
Universal electron acceptors
Hexokinase vs glucokinase
Glycolysis regulation, key enzymes
Regulation by
fructose-2,6-bisphosphate
Pyruvate dehydrogenase complex
PDC defciency
Pyruvate metabolism
TCA cycle (Krebs cycle)
Electron transport chain &
oxidative phosphorylation
Gluconeogenesis, irreversible enzymes
HMP shunt
(pentose phosphate pathway)
Glucose-6-phosphate
dehydrogenase defciency
Disorders of fructose metabolism
Disorders of galactose metabolism
Sorbitol
Lactase defciency
Amino acids
Urea cycle
Transport of ammonia by alanine
Hyperammonemia
Ornithine transcarbamylase
defciency
Amino acid derivatives
Catecholamine synthesis/tyrosine
catabolism
Phenylketonuria
Maple syrup urine disease
Alkaptonuria
Homocystinuria
Cystinuria
Glycogen regulation
by insulin and glucagon/epinephrine
Glycogen
Glycogen storage diseases
Lysosomal storage diseases
Fatty acid metabolism
Ketone bodies
Metabolic fuel use
Lipid transport, key enzymes
Major apolipoproteins
Lipoprotein functions
Abetalipoproteinemia
Familial dyslipidemias


Enzymes

Metabolic Regulation

Energy Metabolism

Carbohydrate Metabolism

Lipid Metabolism

Protein Metabolism

Nucleotide Metabolism
Metabolism


Tissues & Organs


Topics



Links & References


Authors :



Lieberman. BRS Biochemistry, Molecular Biology, and Genetics. 6e. 2013.
Swanson. BRS Biochemistry, Molecular Biology, and Genetics. 5e. 2009.

Ferrier. LIR Biochemistry. 7e. 2017.

Le. First Aid USMLE Step 1. 2017. (Biochelmistry)

Pelley. Rapid Review Biochemistry. 3e. 2010.

Gerhard. Biochemical Pathways : An Atlas of Biochemistry and Molecular Biology 2e. 2012.

Tellingen. Biochemistry - from a phenomenological point of view. 1e. 2001.

Hecketsweiler. Voyage en biochimie : Circuits en biochimie humaine, nutritionnelle et métabolique. 3e. 2006.

Koolman. Atlas of Biochemistry. 3e. 2012.

Salway. Medical Biochemistry at a Glance. 3e. 2012.

Moi : Major Pathways - Lipides Structure