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Pathology - Pathologie - Patologia

Authors :
Robbins Schneider (BRS)
Goljan (RR) Le (First Aid)

Introduction



Cell a Unit Chapter Contents (Robbins)

Healing Process - Phenomenology


Introduction



Methods, Techniques & Diagnoses



Diagnostic techniques
Light microscopy
Histologic stains
Fluorescence microscopy
Electron microscopy
Immunohistochemistry
Flow cytometry
Cytogenetic Analysis
Molecular


Methods, Techniques & Diagnoses


Laboratory Tests




Chapter Contents (Schneider)
Purpose
Operating Characteristics
Predictive Value of Positive &
Negative Results

Creating Highly Sensitive &
Specific Tests

Variables Affecting Results


Laboratory Tests



General Pathology



Cell




Chapter Contents (Schneider)

Chapter Contents (Robbins)
Tissue Hypoxia
Free Radical Cell Injury
Injury to Cellular Organelles
Intracellular Accumulations
Adaptation to Cell Injury: Growth Alterations

Injury


Apoptosis Necrosis

Death



Adaptation


Aging
Amyloidosis


Lipofuscin
Calcifcation


Cell



Inflammation & Repair




Chapter Contents (Schneider)

Chapter Contents (Robbins)
Acute Inflammation
Chronic Inflammation
Tissue Repair
Laboratory Findings Associated
with Inflammation

Inflammation Leukocyte extravasation

Inflammation & Repair Acute inflammation
Acute inflammation :
Clinical features
Chronic inflammation
Granulomatous diseases
Exudate vs Transudate
Erythrocyte sedimentation rate
Amyloidosis
Repair by cell renewal Repair by fibrosis Scar formation Wound healing
Inflammation & Repair



Hemodynamic Disorders




Chapter Contents (Schneider)

Chapter Contents (Robbins)
 

Water & Electrolyte


Acid-Base


Edema


Thrombosis


Embolism


Ischemia


Types of Infarcts


Infarction


Shock


Hemodynamic Disorders


Genetic & Developmental Disorders



Chapter Contents (Schneider)

Chapter Contents (Robbins)
Mutations
Mendelian Disorders
Chromosomal Disorders
Other Patterns of Inheritance
Disorders of Sex Differentiation
Congenital Anomalies
Perinatal & Infant Disorders
Diagnosis of Genetic &
Developmental Disorders

Aging

Genetic diseases
Mechanism of genetic disorders


Genetic & Developmental Disorders


Immunopathology




Chapter Contents (Schneider)

Chapter Contents (Robbins)
Cells of the Immune System
Major Histocompatibility Complex
Hypersensitivity Reactions (HSRs)
Transplantation Immunology
Autoimmune Disease
Immunodeficiency Disorders
Amyloidosis

Immunology Hypersensitivity reactions
Autoimmune diseases
Systemic
Lupus
Erythematous
Tissue transplantation
Immunodeficiency syndromes
AIDS Cancer immunology
Immunopathology


Neoplasia



Chapter Contents (Schneider)

Chapter Contents (Robbins)
Nomenclature
Properties of Benign & Malignant Tumors
Cancer Epidemiology
Carcinogenesis
Carcinogenic Agents
Clinical Oncology
Cellular changes

Neoplastic progression
Tumor grade vs stage
Tumor nomenclature
Cancer epidemiology
Paraneoplastic syndromes
Oncogenes
Tumor suppressor genes
Oncogenic microbes
Carcinogens
Psammoma bodies
Serum tumor markers
Common metastases

Neoplasia
Neoplasia : pathology
Carcinogenesis
Cancer biology
Cancer genes
Neoplasia : clinical aspects
Cancer diagnosis

Neoplasia


Diseases of infancy & childhood



Chapter Contents (Robbins)
Pediatric tumors
Pediatric diseases


Diseases of infancy & childhood


Infectious



Chapter Contents (Robbins)



Infectious


Environment  



Chapter Contents (Schneider)

Chapter Contents (Robbins)
Chemical Injury
Physical Injury
Radiation Injury

Environment 


Nutrition



Chapter Contents (Schneider)
Nutrient & Energy Requirements
in Humans

Dietary Fuels
Protein-Energy Malnutrition
Eating Disorders & Obesity
Fat-Soluble Vitamins
Water-Soluble Vitamins
Trace Elements
Mineral & Electrolyte
Deficiency & Excess

Dietary Fiber
Special Diets


Nutrition


General Pathology



Systemic Pathology


Vascular




Chapter Contents (Schneider)

Chapter Contents (Robbins)
Lipoprotein Disorders
Arteriosclerosis
Vessel Aneurysms
Venous System Disorders
Lymphatic Disorders
Vascular Tumors &Tumor-like Conditions
Vasculitic Disorders
Hypertension

Vasculitis
Aneurysms
Atherosclerosis Hypertension
Vascular



Heart




Chapter Contents (Schneider)

Chapter Contents (Robbins)
Cardiac Physical Diagnosis
Ventricular Hypertrophy
Congestive Heart Failure
Ischemic Heart Disease
Congenital Heart Disease
Acquired Valvular Heart Disease
Myocardial and Pericardial Disorders
Cardiomyopathy
Tumors of the Heart


Heart failure
Valvular heart disease
Infective endocarditis
Rheumatic fever
Myocarditis

Pericardial disease
 
Cardiovascular tumors


Heart



WBC LN Spleen Thymus Marrow



Chapter Contents (Schneider)

Chapter Contents (Robbins)


White Blood Cell Disorders
Benign Qualitative WBC Disorders
Benign Quantitative WBC Disorders
Acute and Chronic Leukemias
Neoplastic Myeloid Disorders
Lymphoid Leukemias
Lymphoid Tissue Disorders
Lymphadenopathy
Non-Hodgkin Lymphoma
Hodgkin Lymphoma
Langerhans Cell Histiocytoses
Mast Cell Disorders
Plasma Cell Dyscrasias
(Monoclonal Gammopathies)

Spleen Disorders


WBC LN Spleen Thymus Marrow



RBC Anemia Bleeding




Chapter Contents (Schneider)

Chapter Contents (Schneider)

Chapter Contents (Robbins)

Red Blood Cell Disorders
Erythropoiesis
Complete Blood Cell Count
& Other Studies

Microcytic Anemias
Macrocytic Anemias
Normocytic Anemias:
Corrected Reticulocyte Count
or Index <3%

Normocytic Anemias:
Corrected Reticulocyte Count >3%
Hemostasis Disorders
Normal Hemostasis &
Hemostasis Testing

Platelet Disorders
Coagulation Disorders
Fibrinolytic Disorders
Summary of Laboratory Test Results
 in Hemostasis Disorders

Thrombosis Syndromes
Immunohematology Disorders
ABO Blood Group Antigens
Rh and Non-Rh Antigen Systems
Blood Transfusion Therapy
Hemolytic Disease of the Newborn

RBC Anemia Bleeding


Respiratory Lung



Chapter Contents (Schneider)

Chapter Contents (Robbins)
Symptoms and Signs of
Respiratory Disease

Alveolar-Arterial (A-a) Gradient
Upper Airway Disorders
Atelectasis
Acute Lung Injury
Pulmonary Infections
Vascular Lung Lesions
Restrictive Lung Diseases
Chronic Obstructive Pulmonary Disease
Lung Tumors
Mediastinum and Pleural Disorders

Respiratory Lung



Head & Neck




Chapter Contents (Robbins)



Head & Neck



Gastrointestinal



Chapter Contents (Schneider)

Chapter Contents (Robbins)
Oral Cavity & Salivary Gland
Esophageal
Stomach
Small Bowel & Large Bowel
Anorectal 

Gastrointestinal


Liver Gallbladder Exocrine Pancreas



Chapter Contents (Schneider)

Chapter Contents (Robbins)

Chapter Contents (Robbins)

Laboratory Evaluation of Liver Cell Injury
Viral Hepatitis
Other Inflammatory Liver Disorders
Circulatory Disorders of the Liver
Alcohol-Related and Drug- and
Chemical-Induced Liver Disorders

Obstructive (Cholestatic) Liver Disease
Cirrhosis
Liver Tumors and Tumor-like Disorders
Gallbladder and Biliary Tract Disease
Pancreatic Disorders



Liver Gallbladder Exocrine Pancreas


Kidney & Urinary Tract



Chapter Contents (Schneider)
Renal Function Overview
Important Laboratory Findings
in Renal Disease

Renal Function Tests
Clinical Anatomy of the Kidney
Congenital Disorders &
Cystic Diseases of the Kidneys

Glomerular Diseases
Disorders Affecting Tubules
& Interstitium

Chronic Renal Failure
Vascular Diseases of the Kidney
Obstructive Disorders of the Kidney
Tumors of the Kidney and Renal Pelvis


Kidney & Urinary Tract


Male



Chapter Contents (Schneider)
Lower Urinary Tract &
Male Reproductive Disorders

Common Ureteral Disorders
Urinary Bladder Diseases
Urethral Diseases
Penis Diseases
Testis, Scrotal Sac,
& Epididymis Diseases

Prostate Diseases
Male Hypogonadism
Male Infertility
Erectile Dysfunction


Male


Female



Chapter Contents (Schneider)
Sexually Transmitted Diseases &
Other Genital Infections

Vulva Disorders
Vagina Disorders
Cervix Disorders
Reproductive Physiology &
Selected Hormone Disorders

Uterine Disorders
Fallopian Tube Disorders
Ovarian Disorders
Gestational Disorders
Breast Disorders


Female


Breast






Breast


Endocrine



Chapter Contents (Schneider)
Overview of Endocrine Disease
Hypothalamus Disorders
Pineal Gland Disorders
Pituitary Gland Disorders
Thyroid Gland Disorders
Parathyroid Gland Disorders
Adrenal Gland Disorders
Islet Cell Tumors
Diabetes Mellitus (DM)
Polyglandular Deficiency Syndromes
Hypoglycemia


Endocrine


Skin



Chapter Contents (Schneider)
Skin Histology and Terminology
Selected Viral Disorders
Selected Bacterial Disorders
Selected Fungal Disorders
Selected Parasitic & Arthropod Disorders
Melanocytic Disorders
Benign Epithelial Tumors
Premalignant &
Malignant Epithelial Tumors

Selected Skin Disorders
Selected Skin Disorders in Newborns
Selected Hair & Nail Disorders


Skin


Bones, Joints & Soft tissue tumors




Chapter Contents (Schneider)
Bone Disorders
Joint Disorders
Muscle Disorders
Soft Tissue Disorders
Selected Orthopedic Disorders


Bones, Joints & Soft tissue tumors



Central & Peripheral nervous system



Chapter Contents (Schneider)
Cerebral Edema, Pseudotumor Cerebri
(Idiopathic Intracranial Hypertension),
Herniation and Hydrocepalus

Developmental Disorders
Head Trauma
Cerebrovascular Diseases
CNS Infections
Demyelinating Disorders
Degenerative Disorders
Toxic & Metabolic Disorders
CNS Tumors
Peripheral Nervous System Disorders
Selected Eye Disorders
Selected Ear Disorders


Central & Peripheral nervous system



Eye


Systemic Pathology


Topics




Links & References





Authors :





Le. First Aid USMLE Step 1. 2017. (Pathology Inflammation & Neoplasia)

Robbins. Pathologic basis of disease. 9e. 2014.

Schneider. BRS Pathology. 5e. 2013.

Goljan. Rapid review pathology. 4e. 2013.

Cheng. Essentials of Anatomic Pathology. 4e. 2016.

Gattuso. Differential diagnosis in surgical pathology. 3e. 2014.

Bie. The healing process Organ of repair. 2008.

Dervan. Mind Maps in Pathology. 2002.

Finlayson. Pathology at a Glance. 1e. 2009.

Chandrasoma. Concise Pathology. 3e. 1997.


Rubin. Clinicopathologic Foundations of Medicine. 7e. 2014. / Essentials of Pathology. 6e. 2013.

Sattar. Pathoma. 1e. 2011. Drafts

Tadrous. Diagnostic Criteria Handbook in Histopathology. 2007.

Riede. Color Atlas of Pathology. 2004.